OUR BLOG

25 Mar 2019
CBD and endometriosis

CBD and Endometriosis; The Relationship

The Unique Role Between CBD and Endometriosis

In today’s society, there are many different expectations, pressures, and stress that affect each of us. Women in particular have overcome numerous challenges, battles, and stereotypes, which continues to this day. What sets women apart from men is not only their biology, but the hormonal changes they undergo month after month. On top of menstruating every month for several decades, millions of women struggle with endometriosis. Endometriosis is a disease of the female menstruation cycle. Although endometriosis is normally a chronic disease, natural remedies can help. Specifically, there is a strong link between CBD and endometriosis. Besides the unique role between CBD and endometriosis, the body’s endocannabinoid system plays a role in this area as well.

The Endocannabinoid System’s Role in Treating Endometriosis

All humans and mammals have an endocannabinoid system (ECS). For us humans, the ECS plays a role in regulating different functions such as the following: secretion of hormones, stress response, food intake, glucose metabolism in muscle cells, lipids synthesis, etc. The endocannabinoid system also helps the human body achieve and maintain homeostasis. According to one report, the elements that are a part of the ECS consist of endocannabinoid receptors (CB1 and CB2), endogenous ligands, enzymes, and cannabinoid antagonists.

As you may already know, CBD does not bind to the CB1 or CB2 receptors like THC does. Instead, CBD interacts with different non-cannabinoid receptors and ion channels. CBD binds to various non-cannabinoid receptors to generate and deliver therapeutic and medical benefits. The delivery of these benefits can be experienced by individuals with endometriosis. CBD and endometriosis have been studied for years to discover how this cannabinoid and the ECS can help treat this female disease.

ECS Imbalances in Endometriotic Women and Levels of CB1 and CB2 Receptors

What role does the ECS play regarding the treatment of endometriosis? So far, certain findings point to an ECS imbalance in endometriotic women. It has also been discovered that there are lower levels of CB1 receptors within endometrial tissue in endometriotic women. On the other hand, it has been revealed that endometriotic women having a higher expression of the CB2 receptor. This may be linked with the body’s natural inflammatory response. As a result, this can lead to endometriotic inflammation and pain.

Furthermore, one study reported the following about endometriosis and the body’s ECS:

“…the endocannabinoid system contributes to mechanisms underlying both the peripheral innervation of the abnormal growths and the pain associated with endometriosis, thereby providing a novel approach for the development of badly-needed new treatments.”

CBD’s Medical Benefits that Can Help Manage Endometriosis Symptoms

The pairing of CBD and endometriosis is quite unique. This is especially because CBD can help deliver analgesic, anti-inflammatory, and other related medical benefits to endometriotic women. Also, when CBD is consumed, it may be able to help treat ECS imbalances. This can be particularly useful for women struggling with painful endometriosis who may have an ECS imbalance.

Although millions of women live with endometriosis, they do not have to live with chronic pain and inflammation. Instead, they can learn more about CBD and endometriosis, and give this cannabinoid a chance as being a natural remedy.

Nicole Skrobin

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