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What is the endocannabinoid system.

What is the Endocannabinoid System, and How Does It Work?

What is the Endocannabinoid System, and do we all have one? If so, how does it work? What are the effects of cannabis when considering the Endocannabinoid System?

We all have an Endocannabinoid System,  also known as the ‘ECS.’ The system is named after the cannabis plant that led to its discovery, and the root of it comes from the Sanskrit word, “Ananda”, which means bliss. The ECS is often categorized as one of the most important physiologic systems involved in establishing and maintaining human health as well as immune responses.

Background of The Endocannabinoid System

In the early-mid 1990s, the ECS was discovered by Ralph Mechoulam and his colleagues. They located and identified two naturally produced major endocannabinoids within the human body. That’s right, we produce our own cannabinoids naturally!

Around the same time, Lisa Matsuda and her team of researchers identified a THC-sensitive receptor within lab rat brains at the National Institute of Mental Health. From this point on, over 20,000 scientific studies have been released in the past two decades regarding the ECS and cannabinoids.

How Does the Endocannabinoid System Work?

As briefly mentioned above, the ECS is important for the human body’s health and equilibrium. The main goal of this system is homeostasis. When your body is able to reach a natural balance, many other health factors come into play.

For those of you who don’t know, homeostasis is the maintenance of a stable internal environment regardless of different fluctuations within the external environment.

The ECS has various integrated mechanisms including the following:

  • Enzymes responsible for creating and destroying cannabinoids
  • Receptor sites on cells to receive cannabinoids
  • Endocannabinoids themselves, which are cannabinoid-like compounds that the human body naturally produces

Overall, each of these mechanisms are responsible for regulating different biological responses through communication within the body. Within the ECS, naturally occurring cannabinoids (endocannabinoids) interact with our bodies.

The ECS is linked to a variety of important processes concentrated within the brain, nervous system, and reproductive organs. Regions of the brain that control heart and lung function aren’t affected.

Endocannabinoids and Cannabinoid Receptors Explained:

The ECS refers to a collection of cell receptors and corresponding molecules, which leads into an important point. The ECS is the name for a series of cell receptors that respond to certain agonists within our bodies.

The primary cell receptors that make up the ECS consist of Cannabinoid Receptor 1 (CB1) and Cannabinoid Receptor 2 (CB2) but more continued to be studied.

Primary endocannabinoid receptors are located throughout the body including; the brain, organs, connective tissues, glands, immune cells, and at the intersection of the body’s different systems. As a result, this allows for communication and coordination between different cell types.

However, specific cannabinoid receptors are more concentrated in certain regions of the body. For example, CB1 receptors are highly abundant within the central nervous system. Whereas, CB2 receptors are on immune cells, in the Gastrointestinal Tract, and within the peripheral nervous system.

Benefits of Endocannabinoid Receptors:

CB1 receptors have a variety of benefits such as; increased appetite, decreased nausea, immune system balance, inhibition of tumors, and modulation of stress and anxiety. On the other hand, CB2 receptors have their own benefits, which includes fighting inflammation and tissue damage.

The Role Endocannabinoids and the ECS Plays:

Endocannabinoids and their receptors are throughout our bodies. The ECS delivers intricate actions that occur within our immune system, nervous system, the body’s organs. It acts as a bridge between our body and mind. However, the role the endocannabinoids and the ECS plays is significant for all of us.

The endocannabinoids that our bodies naturally produce interact with our body’s receptors while transmitting information about changing conditions to kick-start a response. As a result, the body can receive help to achieve homeostasis within itself.

Although our bodies naturally produce endocannabinoids, in some bodies, it’s possible to have difficulty generating enough endocannabinoids, which can lead to an endocannabinoid deficiency syndrome (CECD).

CBD, THC & the ECS:

The relationship these compounds have with endocannabinoids is a unique one. For example, THC binds with the body’s cannabinoid receptors directly, but CBD doesn’t. CBD works indirectly with the receptors within the body’s system, whereas, THC only mimics the body’s naturally produced cannabinoids.

Finally, Take Your Pick!

Now that you’re more familiar with the Endocannabinoid System, or ECS, you can start your CBD journey with Infinite CBD! The first step is identifying an improvement you would like to see in your everyday life. The next step is simply picking a product that you are comfortable with trying.

As starter-products go, we have two that are super simplified and powerful so that “trying CBD” does not become a confusing or uncomfortable task.

First is our Asteroid Gummies. These little morsels come in packs of 5, 10 or 20 and have 25mg of our CBD isolate in each. Second is our Isolate Dropper line, available with terpene and sweetener variations. This tincture bottle makes it easy to incorporate a few drops of CBd into virtually anything! Bound by coconut oil, the potential it has to contribute to your overall health is vast.

• January 7, 2018